When I try to run a certain DirectX app, all of the fonts become garbled. A screenshot is at http://jackmcbarn.no-ip.org/login.png I've already tried setting HKEY_CURRENT_USER\Software\Wine\X11 Driver\ClientSideWithRender to N, which didn't appear to have any effect at all. Increasing the DPI increased the font size, but they were still garbled.
Have you installed all the fonts for WINE? Using Winetricks, have you installed 'allfonts'? r2rX :)