Dear R-experts, Please, excuse me for disturbing... I tried to find the answer to my question in archives without any result... I assume, this is going to look like a stupid question... I have dataset of different brain structures within two groups of subjects. But unfortunately these groups are not matched by age and gender. Would you be so kind to suggest me how (using which formula) can I compare two groups by factor ³diagnosis² considering ³age² and ³gender as nuisance variables? --- Best Regards, Alex [[alternative HTML version deleted]]