R help - Apr 2009 - Package or packages for randomization in a clinical trial

Can anyone recommend a package that can be used to randomize subjects? I am
looking for a generalized package, or several packages that can accomplish
unrestricted randomization (i.e. simple random assignment)
restricted randomization including stratified randomization, blocked
randomization, and adaptive randomization.
Thanks,
John

John David Sorkin M.D., Ph.D.
Chief, Biostatistics and Informatics
University of Maryland School of Medicine Division of Gerontology
Baltimore VA Medical Center
10 North Greene Street
GRECC (BT/18/GR)
Baltimore, MD 21201-1524
(Phone) 410-605-7119
(Fax) 410-605-7913 (Please call phone number above prior to faxing)

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On Apr 21, 2009, at 5:12 AM, John Sorkin wrote:
> Can anyone recommend a package that can be used to randomize  
> subjects? I am looking for a generalized package, or several  
> packages that can accomplish
> unrestricted randomization (i.e. simple random assignment)
> restricted randomization including stratified randomization, blocked  
> randomization, and adaptive randomization.
> Thanks,
> John
John,

Take a look at the 'blockrand' and 'crossdes' packages on CRAN.

If you need something beyond those, it is not overly difficult to  
write functions in R to do this.

HTH,

Marc Schwartz