R help - Feb 2008 - multdrc error---Error in mdrcOpt(opfct, startVec, optMethod, derFlag, constrained, warnVal

Hi,

 

I am newbie of R. I a currently using multdrc object to generate fitting
curve and IC50. My 384 well format raw data contains multi dose response
curves. My script goes through set of data then produce curve and ic50.

 

Here is my sudo code:

 

For (plateid in platelist)

{

Input data (plateid) as matrix

 

Curve fitting

model4logistic <- multdrc(rdata ~ ld, logDose=10)  

}

 

The first 3 plates are ok, 4th plate has following error

Error in mdrcOpt(opfct, startVec, optMethod, derFlag, constrained,
warnVal,  : 

  Convergence failed

 

I know the expected fitting is ugly, is it the reason to produce the
error?

 

Thanks you in advance for your help,

 

Xin Gong

 


	[[alternative HTML version deleted]]

Dear Sir/Madam:

I am newbie of R. I a currently using multdrc object to generate fitting curve
and IC50. My 384 well format raw data contains multi dose response curves. My
script goes through sets of data then produce curve and ic50.

Here is my sudo code:

For (plateid in platelist)
{
Input data (plateid) as matrix
Curve fitting
model4logistic <- multdrc(rdata ~ ld, logDose=10)  
}


The first 3 plates are ok, 4th plate has following error

Error in mdrcOpt(opfct, startVec, optMethod, derFlag, constrained, warnVal,  : 
  Convergence failed

I know the expected fitting is ugly, is it the reason to produce the error?
Any clue about this error message? 

Thanks you in advance for your help,

 
Xin Gong

 



	[[alternative HTML version deleted]]