Sorry for the long message. I'm doing my best to try to explain myself. I have fitted a spline to my data, I have fitted a spline, filled in the missing data by replicating the spline coefficients associated to the last node. I obtained a number of dendograms by different combination of distance and link-method by calling DIST and AGNES. The agglomerative coefficient is very high (~ 0.99) for some combinations, and is generally around 0.5 for the remaining cases. As recommended, I ran the SILHOUETTE at different cuts (CUTREE) for some of the cases. Irregardless of the AC value the highest silhouette width I get is ~ 0.4 or lower, which is too low a level of confidence for accepting any clustering structure, from what I have recently read. My first question is about the use of CUTREE and SILHOUETTE. I've just found in the QA archive a statement about CUTREE expecting an object of type "hclust" as input. Whereas I've always passed an object of type "agnes". I tried to convert the agnes object to an hclust one and carried out the silhouette analysis again, but got the same results. Is such a conversion an important step to get the right answer ? My second doubt is about the angnes parameter STAND. I have centralized and standardized the raw data Iinvolved in the clustering process in advance of fitting a spline. But I have not standardized the actual data I use for clustering, that is the spline coefficients, although I have constantly set the STAND parameter to FALSE. Is this going to affect all my analysis results that may, as a consequence, turned out to be misleading ? In your experience, whenever the agglomerative hierarchical clustering approach does not yield a satisfactory level of confidence about the clustering structure, is it worthwhile to try some Partitioning method ? My question is: if the hierarchical approach does not allow to see any pattern among the data, is the partitioning method a valuable alternative ? If also the Partitioning approach does not reveal any particular data structure. then probably the raw data have to pre-processed further before attempting any clustering at all, or I have chosen the wrong variables in the data set. I'm somehow trying to cluster signal amplitudes that are not referred to the same phase values. For instance, if I have two sinusoids sampled at different phase values like: {sin(0), sin(1/4PI), sin(3/2PI)} and {cos(1/8PI), cos(1/2PI), cos(5/2PI)} is it meaningful to cluster the two set of values above or shall I first refer both signals to the same phase in advance of clustering, like: {sin(0), sin(1/4PI), sin(3/2PI)} and {cos(0I), cos(1/4PI), cos(3/2PI)} or: {sin(1/8PI), sin(1/2PI), sin(5/2PI)} and {cos(1/8PI), cos(1/2PI), cos(5/2PI)} Thank you in advance for your attention. Regards, -- Maura E.M