Matthew L. Fidler
2003-Jan-15 16:57 UTC
[R] Bug or Feature? LogLik.nls and non-central F distribution.
I have a dataset that I am running non-linear regression on via the
following code:
Hill <- function(E0,Em,C50,g,C){
#
# Hill is the hill interaction function.
#
# E0 Represents the minimum interaction Effect
#
# Em Represents the Maximum Interaction Effect
#
# C50 represents the concentration at which 50% of the effect occurs.
#
# gamma represents the cooperativity of the interaction curve.
Somtimes called the hill slope.
#
# C is the concentration of drug.
#
E0 + (Em-E0)*C^g/(C^g+C50^g)
}
short.alif.data <- read.table("shortAlifentanil.txt",header=TRUE);
short.alif.fit <- nls(
formula = E ~ Hill(0,1,A50,g,A),
data = short.alif.data,
start=list(g=1,A50=0.1)
);
Which gives:
> summary(short.alif.fit);
Formula: E ~ Hill(0, 1, A50, g, A)
Parameters:
Estimate Std. Error t value Pr(>|t|)
g 5.689027 1.367207 4.161 0.025247 *
A50 0.093200 0.004438 21.000 0.000236 ***
---
Signif. codes: 0 `***' 0.001 `**' 0.01 `*' 0.05 `.' 0.1 ` '
1
Residual standard error: 0.08848 on 3 degrees of freedom
Correlation of Parameter Estimates:
g
A50 0.1761
> logLik(short.alif.fit);
`log Lik.' 6.307024 (df=1)
My problem with this number is that exp(logLik) > 1. If the error
structure is independent, identically distributed normal (which I
assumed was the case), then the Likelihood function should only give a
number from 0 to 1... I am running R 1.6.1. Perhaps this is due to
some strange assumption of non-independent normals??? Maybe something
else??? I assumed that the Likelihood function should be
-n/2*log(2*pi)-n/2*log(d)-n/2
Where d=MLE (biased) estimator of the variance
My next bug observation is the non-central F distribution:
pf(qf(0.05,1,6-3,lower.tail=FALSE),1,6-3,ncp=1.92,lower.tail=FALSE)
This gives a power of a certain linear model that I have done. However,
the tail is wrong. To get the right answer you should type
pf(qf(0.05,1,6-3,lower.tail=FALSE),1,6-3,ncp=1.92,lower.tail=TRUE)
If one knows the bug, it is easy to get around, but... it shouldn't
return the wrong number.
--
Matthew L. Fidler
fidler at math.utah.edu
421 Wakra Way, Suite 318
Salt Lake City, UT 84108
(801) 581-7125
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Peter Dalgaard BSA
2003-Jan-15 17:26 UTC
[R] Bug or Feature? LogLik.nls and non-central F distribution.
"Matthew L. Fidler" <fidler at math.utah.edu> writes:> > logLik(short.alif.fit); > `log Lik.' 6.307024 (df=1) > > My problem with this number is that exp(logLik) > 1. If the error > structure is independent, identically distributed normal (which I > assumed was the case), then the Likelihood function should only give a > number from 0 to 1...Whatever gave you that idea? Likelihoods can easily be larger than 1 for the same reasons that densitites can. Besides, there is often a multiplicative factor removed from the calculation when it depends on data only.> I am running R 1.6.1. Perhaps this is due to > some strange assumption of non-independent normals??? Maybe something > else??? I assumed that the Likelihood function should be > > -n/2*log(2*pi)-n/2*log(d)-n/2 > > Where d=MLE (biased) estimator of the varianceBut that's unbounded as d goes to zero and log(d) becomes negative! -- O__ ---- Peter Dalgaard Blegdamsvej 3 c/ /'_ --- Dept. of Biostatistics 2200 Cph. N (*) \(*) -- University of Copenhagen Denmark Ph: (+45) 35327918 ~~~~~~~~~~ - (p.dalgaard at biostat.ku.dk) FAX: (+45) 35327907
Matthew L. Fidler
2003-Jan-15 17:38 UTC
[R] Bug or Feature? LogLik.nls and non-central F distribution.
On Wed, 2003-01-15 at 09:18, Douglas Bates wrote:> "Matthew L. Fidler" <fidler at math.utah.edu> writes: > > ... > > > logLik(short.alif.fit); > > `log Lik.' 6.307024 (df=1) > > > > My problem with this number is that exp(logLik) > 1. If the error > > structure is independent, identically distributed normal (which I > > assumed was the case), then the Likelihood function should only give a > > number from 0 to 1... > > Why? The likelihood is the product of the probability densities of > the observations given the parameters and a probability density can be > greater than 1. > > The belief that a likelihood must be less than 1 is a common > misconceptionTrue, if the variance is small (less than one), it can have that feature. I forgot; thank you for reminding me. However I still cannot get the non-central F to return the right tail (according to my linear model's noncentral F distribution tables....) I thought it wasn't working because I couldn't get it to produce the log-liklihood function that I derived. I forgot to divide the residual sum of squares by N, however.... sorry. -- Matthew L. Fidler fidler at math.utah.edu 421 Wakra Way, Suite 318 Salt Lake City, UT 84108 (801) 581-7125 ------------------------------------------------------------------------- Accident, n.: A condition in which presence of mind is good, but absence of body is better. -- Foolish Dictionary -------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: application/pgp-signature Size: 189 bytes Desc: This is a digitally signed message part Url : https://stat.ethz.ch/pipermail/r-help/attachments/20030115/6b1bebb0/attachment.bin