wine users - Jan 2012 - How to compile Wine for best performance?

Hi, I've read that compiling Wine yourself can give better performance than
using the packaged binary. I've tried compiling Wine, but I'm not really
seeing any improvement in performance of Wine on my PC. Is there any
configuration or options I can pass to the compiler to get Wine optimized for my
hardware?

FYI, I'm using Kubuntu 11.10 running on a PC with an AMD A6-3500 triple-core
CPU.