I am newbies and also face the same problem "Warning: No index(es) found! Have you synced your source indexes? " After read an entire thread, I can overcome the problem and think that my explanation will help the others, though this thread is already 10 months-old. In addition, the below steps to put 2 codes were not mentioned in the tutorial by David Baumgold at http://davidbaumgold.com/tutorials/wine-mac/ To solve the problem: First: run the code Code: sudo port selfupdate Second: run this code Code: sudo port sync Ps. to Iamapplenerd: You may use the wrong code. doh123 provided is the correct one. "sudo port selfupdate" but not "sudo port self update" No space between self & update. This is maybe the point that's why you couldn't overcome the problem.