Need some help please I am trying to use this model because I have temporal replication in my data results<-read.table(file=file.choose(),header=T) attach(results) names(results) results<-na.omit(results) library(nlme) library(lattice) results<-groupedData(weight~date|group,outer=~diet,results) plot(results) plot(results,outer=T) model<-lme(weight~diet,random=~date|group,results) everything worked till here although when I compute the model this error appears Error in lme.formula(weight ~ diet, random = ~date | group, results) : nlminb problem, convergence error code = 1 message = iteration limit reached without convergence (9) summary(model) http://n4.nabble.com/file/n948321/rawoctobercalciumexperiment2.xlsx rawoctobercalciumexperiment2.xlsx kind regards thank you in advance Ana -- View this message in context: http://n4.nabble.com/pseudoreplication-LME-tp948321p948321.html Sent from the R help mailing list archive at Nabble.com.