For a fitted Cox model, one can either produce the predicted survival curve for a particular "hypothetical" subject (survfit), or the predicted curve for a particular cohort of subjects (survexp). See chapter 10 of Therneau and Grambsch for a long discussion of the differences between these, and the various pitfalls. By default, survfit produces the curve for a hypothetical "average" subject whose covariate values are the respective means of the data set. I'm not very keen on this estimate --- what is sex=.453, a hermaphrodite? But it is the historical default. Terry Therenau ---- begin included message ------------- I am confused when trying the function survfit. my question is: what does the survival curve given by plot.survfit mean? is it the survival curve with different covariates at different points? or just the baseline survival curve? for example, I run the following code and get the survival curve #### library(survival) fit<-coxph(Surv(futime,fustat)~resid.ds+rx+ecog.ps,data=ovarian) plot(survfit(fit,type="breslow")) summary(survfit(fit,type="breslow")) #### for the first two failure points, we have s(59|x1)=0.971, s(115|x2)=0.942 how can we guarantee that s(59|x1) is always greater than s(115|x2)? since s(59|x1)=s_0(59)^exp(\beta'x1) and s(115|x2)=s_0(115)^exp(\beta'x2), we can manipulate covariates to make s(59|x1) < s(115|x2), right? do I miss anything? thanks in advance