For a lark, I experimented a bit with the data from Ted Byers' recent postings. The result of fitdistr() seemed sensible, but I was bothered by the warnings about NaNs that arose. Warnings always make me nervous. Explicitly this is what I did: TXT <- "0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 3 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 7 7 7 7 7 7 7 7 7 7 7 7 7 7 8 8 8 8 9 9 9 9 9 9 9 9 9 10 10 10 10 10 10 10 10 10 11 11 11 11 11 11 11 11 11 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 18 18 18 18 18 18 18 18 18 18 18 18 18 18" x <- scan(textConnection(TXT)) closeAllConnections() try.x <- fitdistr(x,"negative binomial") Two warnings about NaNs being produced resulted. Digging into the code with browser() revealed that in the optimization process negative values of "size" were tried on occasion, and this was giving the NaNs. Basically I'm sending this out so that maybe those who are like me and are made nervous by warnings will be able to search the archives and find reassurance that all is actually well. To keep the warnings from the door, one can set an argument "lower" in the call to fitdistr, e.g. eps <- sqrt(.Machine$double.eps) fitdistr(x,"negative binomial",lower=c(eps,eps)) Note that setting lower=c(0,0) doesn't work --- you get an *error* to the effect that L-BFGS-B needs finite values of 'fn'!!! I also tried building my own local version of fitdistr() which had if(distname == "negative binomial" & is.null(Call$lower)) Call$lower <- rep(sqrt(.Machine$double.eps),2) just after the assignment ``Call$hessian <- TRUE''. This *seemed* to work (i.e. prevent those nervous-making warnings and still give the right answer). cheers, Rolf Turner ###################################################################### Attention:\ This e-mail message is privileged and confid...{{dropped:9}}