dear R users, I need some help for multivariate analysis. I have 2 anaesthetic treatment groups (20 patients/group) where I register heart frequency and pressure for 60 min (repeated measures every 5 minutes). I would like to perform a test to check if treatments are different in controlling freq and pressures during the anaesthesia, but i would like to have also an overall measure and not only multiple p for different time intervals. I also think I should choose a test in which time is meaningful since the measures are not simple repeated measurements but measurements taken at specific time points. 1 million dollar question.... how to do in R? thanks in advance Dr Matteo Vidali Dep. of Medical Sciences University of East Piedmont "A. Avogadro" ITALY --