Hi all, I'm a PhD student at sydney uni and am trying to run a non linear mixed model program to obtain estimates of parameters describing dairy cow lactation curves. At present, I have been able to get the data to converge using the S plus (S plus 2000) nlme function. However, when I put the same data into R (R 1.9.0), add in the nlme package and run the code, it does not converge by the max 50 iterations. Is this because the nlme function is slightly different and if so, is there a way to solve this problem? The code I am using is below: W3<-deriv(~A*ti^exp(logB)*exp(-exp(logC)*ti),c("A","logB","logC"), function(ti,A,logB,logC){}) Lact.nlme<-{nlme(model=MLKYLD~W3(DIM,A,logB,logC), fixed=A+logB+logC~1, random=A+logB+logC~1|ID, data=LacData.x0, start=c(13.41143,log(0.152792),log(0.002494)), control=nlmeControl(msMaxIter=200), verbose=T) } Any help or advice would be greatly appreciated, Evelyn -- Evelyn Hall PhD Student Faculty of Veterinary Science C01 JL Shute Building Camden University of Sydney