Dear R: I am trying to fit a doubly multivariate LME (DM) where I have two response variables measured on two occasions per person. Specifically, reading and math scores measured at the beginning and ending of a school year. The response variables have a correlation of r = .85. The response variables in the data matrix are stacked in a vector with a dummy code flagging each outcome and with time variables for each outcome. The model was fit by removing the overall intercept, but creating fixed effects and random effects for each using the following: mult2.lme<-lme(fixed=score~-1+read+math+time.m+time.r, data=mult.samp, random=~-1+read+math+time.r+time.m|childid) This worked and seemed to produce reasonable estimates. I then ran a model using only a single outcome (reading) and found that the estimates are very similar, so I am relatively confident in the results of the model. Now, I have a couple of questions regarding the DM LME: 1) If I wanted to explore model assumptions, i.e., homoscedasticity and dependence among the residuals, how might I do this. For example, how might I specify an AR1 structure? I have explored the assumptions in the single response model, but am having trouble now. 2) I presume it is safe to explore the intercepts and slopes using lmList () one variable at a time. Is this correct? 3) The AIC statistic for the single response model is half the size of the DM model. It is my understanding that this statistic is more appropriate than LL test in this scenario. Is this correct? If so, is there a reason that may explain the larger AIC in the DM model? Or, is this indicating that the single response model is a better fit? 4) Last, is there any other issue that I am missing? I may not have asked the question, but would appreciate any suggestions related to the model. Regards, ------ Harold C. Doran Director of Research and Evaluation New American Schools 675 N. Washington Street, Suite 220 Alexandria, Virginia 22314 703.647.1628 <http://www.edperform.net/> [[alternative HTML version deleted]]