zfs discuss - Dec 2008 - mismatched replication level question

When I attempt to create a 46 disk pool with 5 and 6 disk raidz vdevs, I get
the following message:

mismatched replication level: both 5-way and 6-way raidz vdevs are present
mismatched replication level: both 6-way and 5-way raidz vdevs are present

I expect this is correct.[1]  But what does it mean for performance or other
issues? Why am I being warned?

The factory config for x4500s had the a raidz 5 and 6 disk vdev layout.

[1] http://docs.sun.com/app/docs/doc/819-5461/gazgc?a=view
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