Got exactly the same issue as you. did you sort it out? in addition to your error I had this error at the IMA.methy450PP stage I got this: Warning message: In if (snpfilter != FALSE) { : the condition has length > 1 and only the first element will be used -- View this message in context: http://r.789695.n4.nabble.com/R-IMA-sitetest-problem-tp4643126p4648252.html Sent from the R help mailing list archive at Nabble.com.