I wouldn't put too much stock in the braggings of an ad-ware author.
Let's see what happens when he sticks a null in the middle of the Wine
registry.
People use Wine to run "must-have" or
"no-equivalent-Linux-program" applications like productivity suites
and games. There's very little reason to install some crapware screensaver
or the other apps typically bundled with adware.
And, if Wine does get infected (which would say something good about its
compatibility), just blow away the prefix and either recreate it or restore it
from a backup (BackupPC rocks!). Installing different apps into their own
prefixes makes this even easier. And, it's not near the hassle that people
go through when a Windows box gets owned.