search for: pkpd

Dear all, I have two questions: 1. Does anyone know if nlmeODE package will work once odesolve is discontinued? If i understand well nlmeODE depends on odesolve. 2. Can anyone suggest another package I could use to fit complex PKPD models (described using differential equations) to data? Thanks a lot! Magdalena

Post-Doctoral Fellowship Modelling of Cardiovascular Safety (full time) Leiden University, Leiden, The Netherlands <javascript:doredirect();> Job description TOP Institute Pharma (TI Pharma) has granted our proposal to set up a mechanism-based PKPD modelling platform. This platform focuses on the transfer of knowledge from academia to the pharmaceutical industry and is a collaborative effort of four excellent academic institutes and six leading global pharmaceutical industries. Unique to this platform is the availability of shared databases o...

TOP Institute Pharma (TI Pharma) has granted our proposal to set up a mechanism-based PKPD modelling platform. This platform focuses on the transfer of knowledge from academia to the pharmaceutical industry and is a collaborative effort of four excellent academic institutes and six leading global pharmaceutical industries. Unique to this platform is the availability of shared databas...

...rs. Unique to this platform is the availability of shared databases on disease and drug related parameters. The aim of the platform is to provide a scientific basis for rational drug discovery and development with a strong focus on priority medicines. Challenges are 1) to develop mechanism-based PKPD models to characterise disease progression and to predict the effects of ageing on clinical response and 2) to create a translational research framework that allows extrapolation of preclinical to clinical and epidemiological findings. Existing (pre-) clinical data will be analysed with advanced da...

...0.05, just=c(0,0))) grid.text(label = i, just = c("centre","centre"), gp = gpar(fontsize = 10, font = 2)) popViewport() # Updates isnewpage # isnewpage <- TRUE } -- *Sebastien Bihorel, PharmD, PhD* PKPD Scientist Cognigen Corp Email: sebastien.bihorel at cognigencorp.com <mailto:sebastien.bihorel at cognigencorp.com> Phone: (716) 633-3463 ext. 323

...pad2=1), right=list(tck=1, pad1=1, pad2=1))) print(plot1) dev.off() ########################### -- *Sebastien Bihorel, PharmD, PhD* PKPD Scientist Cognigen Corp Email: sebastien.bihorel at cognigencorp.com <mailto:sebastien.bihorel at cognigencorp.com> Phone: (716) 633-3463 ext. 323

...ackground job notifier i find error messages like this one below.** **Does anyone know how to proceed from here?** **bram** * *Importing report report-1540-1.yaml* at *2011-09-05 11:49 UTC* Permission denied - /usr/share/puppet-dashboard/spool/report-1540-1832.yaml Backtrace <http://puppetmaster.pkpd.gorlaeus.net:3000/delayed_job_failures> /usr/share/puppet-dashboard/app/models/report.rb:86:in `read'' /usr/share/puppet-dashboard/app/models/report.rb:86:in `create_from_yaml_file''* * -- You received this message because you are subscribed to the Google Groups "Puppet U...

________________________________ Principal Post-Doctoral Fellow PKPD modelling platform (full time) Leiden University, Leiden, The Netherlands <javascript:doredirect();> Job description ________________________________ TOP Institute Pharma (TI Pharma) has granted our proposal to set up a mechanism-based PK-PD modelling platform. This platform focu...

Dear R-users, The sasxport.get function (from the Hmisc package) automatically defines the class of imported variables. I have noticed that the class of theoretically numeric variables is simply "labelled", although character variables might end up been defined as "labelled" "Date" or "labelled" "factor". Is there a way to tell sasxport.get to

Dear developer this softwere is very much useful thanks for the everyones availability first. I need the programm to run an IVIVC for an IR BCS class 2 product. I have dissolution upto 45 mins and plasma profile upto 72 hours. For test and reference products of pilot study which is actually failed for cmax parameter. To predict the upcoming formulations of the same product with varying release

...s situation and code. Basically, I would like to have 10 different colors of line and pch(line and pch will be in same color) for each combination of ID and DID. I expected first 10 colors in R for this plot initially. I appreciate your instructions. dogpbmc=read.table('E:\\MPI\\4924\\PBMC-PKPD\\mpbmc.tab', skip=1, header=T) dogpbmc=dogpbmc[dogpbmc$MDV!=1,] par(mfrow=c(2,2),mar=c(5,5,4,4)) # E vs t for simultaneous modeling temp.col=0 for (i in unique(dogpbmc$ID)){ j=dogpbmc$ID==i plot(dogpbmc$TIME[j], dogpbmc$DV[j], type='n', xlim=c(0,max(dogpbmc$TIME[j&dogpbmc$CMT==4])+1...