Hi there! I have huge datafile of 600 columns 360 samples: data <- read.table("small.txt", header = TRUE, sep = "\t", dec = ".", row.names=1) The txt.file (compiled with excel) is showing me only numbers, however R gives me the structure of ANY column as "factor". When i try "stringsAsFactors=FALSE" in the read command, the structure of the dataset becomes "character." When i try as.numeric(data), i get Error: (list) object cannot be coerced to type 'double' even, if i try to subset columns with []. When i try as.numeric on single columns with $, i am successful, but the numbers dont make any sense at all, as the factors are not converted by their levels: Factor w/ 358 levels "0,123111694",..: 11 14 50 12 38 44 13 76 31 30 becomes num 11 14 50 12 38 44 13 76 31 30 whereas i would need the levels, though! I suspect excel to mess up the "save as tab-delimited text", but the text file seems fine with me on surface (i dont know how the numbers are stored internally). I just see correct numbers, also the View command yields the correct content. Anyone knows help? Its pretty annoying. Thank you! -- Tim Richter-Heitmann [[alternative HTML version deleted]]