Dear List, After updating to R 3.10 and Bioconductor 2.14, I'm having a rather frustrating error whenever I try using function like cairo_ps to save eps figures as demonstrated in the following example: cairo_ps('test.eps') plot(c(1:10),c(1:10)) Fontconfig error: Cannot load default config file dev.off() The plot displays distorted text (attached), and I just couldn't figure out where the fix is after google for hours. Any helps will be very much appreciated. Many thanks, Yue