Dear list members: I am using the package fdrtool to calculate qval from my input p values. My input pvalue ranged from 0.5-0. And the result I got for qval and lfdr are all much less than 0.01, I feel very confused about the result. The command used there is very easy: fdrtool(pvalue, statistic="pvalue") I am wondering if it is caused by the range of my pvalue or something else. If you have any similar experience, could you please share it with me? I will appreciate your comments very much! Best regards Li [[alternative HTML version deleted]]