Dear All, I am running R in a system with the following configuration *Processor: Intel(R) Xeon(R) CPU X5650 @ 2.67GHz OS: Ubuntu X86_64 10.10 RAM: 24 GB* The R session info is * R version 2.14.1 (2011-12-22) Platform: x86_64-pc-linux-gnu (64-bit) locale: [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8 [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8 [7] LC_PAPER=C LC_NAME=C [9] LC_ADDRESS=C LC_TELEPHONE=C [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C * I have a matrix of dimensions 12 rows X 29318 columns. The matrix contains numeric as well as NA values. I am using the* rcorr *function from the * Hmisc* package to get correlation information from the matrix (* rcorr(matrix)*). During the calculation I get the error "*cannot allocate vector of size 6.7 GB*". When I check the memory allocation of my R session I get the following information *gc() used (Mb) gc trigger (Mb) limit (Mb) max used (Mb) Ncells 249638 13.4 467875 25.0 NA 407500 21.8 Vcells 1499217 11.5 2335949 17.9 7000 1970005 15.1 *Can someone please help me in finding a workaround to the problem. -Regards -- Swaraj Basu PhD Student (Bioinformatics - Functional Genomics) Animal Physiology and Evolution Stazione Zoologica Anton Dohrn Naples [[alternative HTML version deleted]]