R help - Nov 2011 - Power analysis and sample size calculation for nonlinear regression

Is there a library that provides power calculation and sample size  
estimation for nonlinear regression?

The task is easy for linear regression with the "pwr" package, but I  
can't find a method for nonlinear regression (estimated with the
"nls"
package).

-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --  
-- --
-- Dr. Johannes W. Dietrich, M.D.
-- Laboratory XU44, Endocrine Research
-- Medical Hospital I, Bergmannsheil University Hospitals
-- Ruhr University of Bochum
-- Buerkle-de-la-Camp-Platz 1, D-44789 Bochum, NRW, Germany
-- Phone: +49:234:302-6400, Fax: +49:234:302-6403
-- eMail: "j.w.dietrich@medical-cybernetics.de"
-- WWW: http://medical-cybernetics.de
-- WWW: http://www.bergmannsheil.de
-- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --  
-- --



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May I suggest you consult your local statistician. For reasons that (s)he
can answer, your request makes little sense.

Hint: Nonlinear regression is much different than linear regression: The
design matrix -- and hence the variance of estimators -- is a function of
the parameters being estimated.

(But there may well be packages that are relevant -- the issue is your
ability to use them properly)

Cheers,
Bert



On Mon, Nov 14, 2011 at 10:52 AM, Johannes W. Dietrich <
johannes.dietrich@ruhr-uni-bochum.de> wrote:
> Is there a library that provides power calculation and sample size
> estimation for nonlinear regression?
>
> The task is easy for linear regression with the "pwr" package,
but I
> can't find a method for nonlinear regression (estimated with the
"nls"
> package).
>
> -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
> -- --
> -- Dr. Johannes W. Dietrich, M.D.
> -- Laboratory XU44, Endocrine Research
> -- Medical Hospital I, Bergmannsheil University Hospitals
> -- Ruhr University of Bochum
> -- Buerkle-de-la-Camp-Platz 1, D-44789 Bochum, NRW, Germany
> -- Phone: +49:234:302-6400, Fax: +49:234:302-6403
> -- eMail: "j.w.dietrich@medical-cybernetics.de"
> -- WWW: http://medical-cybernetics.de
> -- WWW: http://www.bergmannsheil.de
> -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- --
> -- --
>
>
>
>        [[alternative HTML version deleted]]
>
> ______________________________________________
> R-help@r-project.org mailing list
> https://stat.ethz.ch/mailman/listinfo/r-help
> PLEASE do read the posting guide
> http://www.R-project.org/posting-guide.html
> and provide commented, minimal, self-contained, reproducible code.
>


-- 

Bert Gunter
Genentech Nonclinical Biostatistics

Internal Contact Info:
Phone: 467-7374
Website:
http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm

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