Good morning, I have a time serie of clinical data. I know, from the literature, that it must have a linear trend, without seasonal oscillations. Can I use LOESS to have a qualitative confirm? I have only 15 mensurations: how should I choose the smoothing parameter? Thanks, best reguards Stefano Giampiccolo -- View this message in context: http://r.789695.n4.nabble.com/data-smoothing-tp3430797p3430797.html Sent from the R help mailing list archive at Nabble.com.