Dear all, I would like to apply Orthogonal Projections to Latent Structures Discriminant Analysis (OPLS-DA) to a metabolomic dataset, in order to discriminate two groups of samples. I have looked for an available R package and I have found "K-OPLS" and oscorespls.fit (Orthogonal scores PLSR) from "pls" package. I wonder if K-OPLS performs the same discriminant analysis of OPLS-DA? Is there any other available package for applying OPLS-DA? Thanks in advance for any advice. Best regards, Francesca Chignola -- ------------------------------- Francesca Chignola, PhD Dulbecco Telethon Institute c/o S. Raffaele Scientific Institute Center of Genomics, BioInformatics and BioStatistics Biomolecular NMR Laboratory 1B4 Via Olgettina 58 20132 Milano Italy ----- ------------------------------------------------------------- DAI IL TUO 5 X MILLE AL SAN RAFFAELE. BASTA UNA FIRMA. SE FIRMI PER LA RICERCA SANITARIA DEL SAN RAFFAELE DI MILANO, FIRMI PER TUTTI. C.F. 03 06 42 80 153 INFO: 5permille at hsr.it - www.5xmille.org