Hello, I have I problem and I hope someone can help me. I have a data set with 66 variables and 30 values for each variable. I need to calculate the Pearson correlation and the p-values among variables. I have the ?large p, small n? problem so I used a shrinkage process to obtain the r values. My problem is that I can?t calculate the p-values because the degree of freedom of the t-student distribution is: df=30-66-1, It is negative and the t-student distribution is not defined for negative degrees of freedom. Is there some way to calculate the p-value in the ?large p, small n? problem? Thank you all in advance. -- View this message in context: http://www.nabble.com/rromero3000-tp25295268p25295268.html Sent from the R help mailing list archive at Nabble.com.