Dear ALL, In the Normal Linear Mixed Model (NLMM) we make the assumption that the random effects are normally distributed. Is it possible to fit a linear mixed model in R where the random effects are assumed to have a Skew-Normal distribution? I am trying to reproduce the results in the paper referenced below. Can anyone help? Tsung I. Lin, Jack C. Lee. Estimation and prediction in linear mixed models with skew-normal random effects for longitudinal data. Statistics in Medicine 2008; 27 (9):1490?1507 Regards, Raphael -- Raphael A. Fraser, MSc Lecturer in Biostatistics Tropical Medicine Research Institute Faculty of Medical Sciences University of the West Indies Mona Campus Kingston, JAMAICA Tel: ?(876) 927-2471; 977-6151 Mobile: (876) 410-4699 Fax: (876) 927-2984 e-mail: raphael.fraser at uwimona.edu.jm
Dear ALL, In the Normal Linear Mixed Model (NLMM) we make the assumption that the random effects are normally distributed. Is it possible to fit a linear mixed model in R where the random effects are assumed to have a Skew-Normal distribution? I am trying to reproduce the results in the paper referenced below. Can anyone help? Tsung I. Lin, Jack C. Lee. Estimation and prediction in linear mixed models with skew-normal random effects for longitudinal data. Statistics in Medicine 2008; 27 (9):1490?1507 Regards, Raphael -- Raphael A. Fraser, MSc Lecturer in Biostatistics Tropical Medicine Research Institute Faculty of Medical Sciences University of the West Indies Mona Campus Kingston, JAMAICA Tel: ?(876) 927-2471; 977-6151 Mobile: (876) 410-4699 Fax: (876) 927-2984 e-mail: raphael.fraser at uwimona.edu.jm
See sn.em in the sn package. Bert Gunter Genentech Nonclinical Biostatistics -----Original Message----- From: r-help-bounces at r-project.org [mailto:r-help-bounces at r-project.org] On Behalf Of Raphael Fraser Sent: Tuesday, July 28, 2009 9:22 AM To: r-help at r-project.org Subject: [R] Skew-Normal Linear Mixed Model (SNLMM) Dear ALL, In the Normal Linear Mixed Model (NLMM) we make the assumption that the random effects are normally distributed. Is it possible to fit a linear mixed model in R where the random effects are assumed to have a Skew-Normal distribution? I am trying to reproduce the results in the paper referenced below. Can anyone help? Tsung I. Lin, Jack C. Lee. Estimation and prediction in linear mixed models with skew-normal random effects for longitudinal data. Statistics in Medicine 2008; 27 (9):1490?1507 Regards, Raphael -- Raphael A. Fraser, MSc Lecturer in Biostatistics Tropical Medicine Research Institute Faculty of Medical Sciences University of the West Indies Mona Campus Kingston, JAMAICA Tel: ?(876) 927-2471; 977-6151 Mobile: (876) 410-4699 Fax: (876) 927-2984 e-mail: raphael.fraser at uwimona.edu.jm ______________________________________________ R-help at r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.