Hello, Much like Charlie Wills a year ago, I am trying to run the APE program COMPAR.GEE with a model containing a categorical response variable and a continuous variable. My command code is : compar.gee(costusdata$Syndrome ~ costusdata$Stamen, phy = costustree, family = "binomial") I receive the following output with an error: Beginning Cgee S-function, @(#) geeformula.q 4.13 98/01/27 running glm to get initial regression estimate (Intercept) costusdata$Stamen18 costusdata$Stamen20.5 costusdata$Stamen22.5 costusdata$Stamen25.5 costusdata$Stamen27.5 costusdata$Stamen28 2.056607e+01 -3.750463e-08 -5.619142e-08 -5.644906e-08 -3.849581e-08 -5.622864e-08 -3.777595e-08 costusdata$Stamen30 costusdata$Stamen31 costusdata$Stamen32 costusdata$Stamen32.5 costusdata$Stamen35 costusdata$Stamen36.5 costusdata$Stamen37 -3.954765e-08 -3.749803e-08 -4.113214e +01 -1.917977e+01 -3.748004e-08 -4.113214e +01 -5.282325e-08 costusdata$Stamen37.5 costusdata$Stamen38.5 costusdata$Stamen39 costusdata$Stamen41.3 costusdata$Stamen42.5 costusdata$Stamen45 costusdata$Stamen47.5 -5.584079e-08 -4.113214e+01 -4.113214e +01 -5.272208e-08 -2.016060e+01 -4.113214e +01 -4.113214e+01 costusdata$Stamen50 costusdata$Stamen52.5 costusdata$Stamen55 costusdata$Stamen? -4.113214e+01 -4.113214e+01 -5.309908e-08 -2.264551e+01 Error in gee(costusdata$Syndrome ~ costusdata$Stamen, c(1, 1, 1, 1, 1, : Cgee: error: logistic model for probability has fitted value very close to 1. estimates diverging; iteration terminated. Simon Blumberg answered Charlie's issue with "My guess is that this combination of variables produces separation in the data: Too many (all?) of the response 1's are in at level of VAR3, and the 0's are at the other level (or vice versa)." I only have the two variables. I'm wondering if anyone has encountered this problem and how you went about solving it. I believe that the problem appears when one has to low (phylogenetic) replication within each (pollination mode) factor level. Is there a way to run compar.gee if this is in fact the problem. From the data, I want to know if there a decrease in the continuous trait is correlated with a change in the categorical trait. Any insight is much appreciated. Thank you, Jenn [[alternative HTML version deleted]]