Dear R users, I?m trying to optimize simultaneously two binomials inequalities used to acceptance sampling, which are nonlinear solution, so there is no simple direct solution. The 'n' represents the sample size and the 'c' an acceptance number or maximum number of defects (nonconforming) in sample size. The objective is to obtain the smallest value of 'n' (sample size) satisfying both inequalities: (1-alpha) <= pbinom(c, n, p1) && pbinom(c, n, p2) <= beta --> where p1 and p2 are probabilities (Consumer and Producer risks); Considering that the 'n' and 'c' values are integer variables, it is commonly not possible to derive an OC curve including the both (p1,1-alpha) and (p2,beta) points. Some adjacency compromise is commonly required, achieved by searching a more precise OC curve with respect to one of the points. I?m using Mathematica 6 but it is a Trial, so I would like use R intead (better, I need it)! In Mathematica I call a parameter called restriction: // fucntion name "findOpt" and parameters... restriction = (1 - alpha) <= CDF[BinomialDistribution[sample_n, p1], c] && betha >= CDF[BinomialDistribution[sample_n, p2], c] && 0 < alpha < alphamax && 0 < betha < bethamax && 1 < sample_n <= lot_Size && 0 <= c < amostra && p1 < p2 < p2max ; fcost = sample_n/lot_Size; result = NMinimize[{fcost, restriction}, {sample_n, c, alpha, betha, p2max}, Method -> "NelderMead", AccuracyGoal -> 10]; example: findOpt[0.005, 1000, 0.05, 0.05, 0.04] ==> and I got the return of values of; "n", "c", alpha and betha, computed. {0.514573, {alpha$74 -> 0.0218683, sample_n$74 -> 155.231, betha$74 -> 0.05, c$74 -> 2, p2$74 -> 0.04}} .:. Note that I?m using lot_Size because I'm using hypergeomtric in some situations... Using R, I would define the "pbinom(c, n, prob)" given only the minimum and maximum values to "n" and "c" and limits to p1 and p2 probabilities (Consumer and Producer). The optimize I could define only using the p1 point, because the "n" and "c" values, are integers and I couldn?t run the example like in mathematica. Could anyone help me Thank you very much. Emir Toktar emir.toktar at computer.org