Now that we have case cohort model , we have 1000 people and 50 cases Let the first 10 cases occur at the same time second 10 " third 10 " fourth 10 " fifth 10 " How easy is it to randomly sample 50 different cohort controls for each group? That is: randomly sample 50 cohort controls for the first 10 cases from all 1,000 randomly sample 50 new cohort controls for the second 10 cases from the surviving 990 randomly sample 50 new cohort controls for the third 10 cases from the surviving 980 randomly sample 50 new cohort controls for the fourth 10 cases from the surviving 970 randomly sample 50 new cohort controls for the fourth 10 cases from the surviving 960 and run these through a time dependent COX-PH? [[alternative HTML version deleted]]