Hi All, I tried to install AnnotationDBI like so: source("http://bioconductor.org/biocLite.R") biocLite("AnnotationDbi") and got this error: .... Loading required package: RSQLite Error in dyn.load(file, ...) : unable to load shared library '/RHEL3/local/lib64/R/library/ RSQLite/libs/RSQLite.so': /RHEL3/local/lib64/R/library/RSQLite/libs/RSQLite.so: undefined symbol: sqlite3_bind_int Error: package 'RSQLite' could not be loaded Execution halted ERROR: lazy loading failed for package 'AnnotationDbi' ** Removing '/RHEL3/local/lib64/R/library/AnnotationDbi' The downloaded packages are in /RHEL3/tmp/Rtmp6ex1Pz/downloaded_packages Updating HTML index of packages in '.Library' Warning message: In install.packages(pkgs = pkgs, repos = repos, dependencies = dependencies, : installation of package 'AnnotationDbi' had non-zero exit status > However, I did install RSQLite and the installation finished with no errors. But: > require(RSQLite) Loading required package: RSQLite Error in dyn.load(file, ...) : unable to load shared library '/usr/local/lib64/R/library/RSQLite/ libs/RSQLite.so': /usr/local/lib64/R/library/RSQLite/libs/RSQLite.so: undefined symbol: sqlite3_bind_int The library and file do exist with 755 permissions. My session info: > sessionInfo() R version 2.6.2 (2008-02-08) x86_64-unknown-linux-gnu locale: LC_CTYPE=en_US.UTF-8;LC_NUMERIC=C;LC_TIME=en_US.UTF-8;LC_COLLATE=en_US.U TF-8;LC_MONETARY=en_US.UTF-8;LC_MESSAGES=en_US.UTF-8;LC_PAPER=en_US.UTF- 8;LC_NAME=C;LC_ADDRESS=C;LC_TELEPHONE=C;LC_MEASUREMENT=en_US.UTF-8;LC_ID ENTIFICATION=C attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] DBI_0.2-4 loaded via a namespace (and not attached): [1] rcompgen_0.1-17 tools_2.6.2 > Has anyone a clue? I am not a R user, just the IT person who has to install it, so if you need additional info from inside R, please let me know how to get it. Thanks a lot, Maya [[alternative HTML version deleted]]