R help - Mar 2007 - Optimal workstation architecture for running R / Bioconductor

Dear list,

I use a lot of data files (at the moment 35 files by 34 MB each) for analysis. 
My own processing steps  will (hopefully) improve with increasing number of
files I have.
So I am looking for an suitable workstation configuration, e.g. 64bit
architecture, 16 GB RAM.... etc.

Does anyone have any experience with setting up such a system ?

Gunther