Hello, I have R for Mac OS X Aqua GUI Version 1.14 with R 2.2.0 Framework. I got following warnings when installing "qtl" package 1.01-9 from CRAN (sources) on the austrian mirror: warning 1: ld: warning multiple definitions of symbol _signgam /Library/Frameworks/R.framework/../R.framework/R(lgamma.lo) definition of _signgam /usr/lib/libSystem.dylib(gamma9.o) definition of _signgam warning 2: perl: warning: Setting locale failed. perl: warning: Please check that your locale settings: LC_ALL = (unset), LANG = "en_CZ.UTF-8" are supported and installed on your system. perl: warning: Falling back to the standard locale ("C"). warning 3: chmod: /Library/Frameworks/R.framework/Versions/2.2/Resources/library/ R.css: Operation not permitted Two of them - warnings 2 and 3 - I get quite often, also with other packages, they seem to be a systemic problem. Any suggestions? Thank you much. Regards, Radek Radek Blatny, MSc. Institute of Molecular Genetics Department of Mouse Molecular Genetics (Jiri Forejt unit) Czech Academy of Sciences Videnska 1083 142 20, Prague Czech Republic Tel. (+420) 241 062 256 Fax (+420) 241 062 154 http://www.img.cas.cz/mmg email: blatny at biomed.cas.cz Skype name: blatny