Dear list members, how can multiple imputation realized for anova tables in R? Concretely, how to combine F-values and R^2, R^2_adjusted from multiple imputations in R? Of course, the point estimates can be averaged, but how to get standarderrors for F-values/R^2 etc. in R? For linear models, lm.mids() works well, but according to Rubins rules, standard errors have to be used together with the estimates to get unbiased estimates. The same is needed for lme models. For the regression coefficients of lme, it is no problem, because s.e.'s are present. But how to combine AIC/ BIC,loglik and especially how to proceed with the random effects in lme's? I assume there is a general rule which can be applied to all these cases, but I do not get it right. e.g. > anova(limo1) Analysis of Variance Table Response: lverb.ona Df Sum Sq Mean Sq F value Pr(>F) klasse 6 301.6 50.3 2.0985 0.05514 . Residuals 193 4623.3 24.0 --- Signif. codes: 0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1 or (from the manpage of lme) > summary(fm2) Linear mixed-effects model fit by REML Data: Orthodont AIC BIC logLik 447.5125 460.7823 -218.7563 Random effects: Formula: ~1 | Subject (Intercept) Residual StdDev: 1.807425 1.431592 Fixed effects: distance ~ age + Sex Value Std.Error DF t-value p-value (Intercept) 17.706713 0.8339225 80 21.233044 0.0000 age 0.660185 0.0616059 80 10.716263 0.0000 SexFemale -2.321023 0.7614168 25 -3.048294 0.0054 Correlation: (Intr) age age -0.813 SexFemale -0.372 0.000 Standardized Within-Group Residuals: Min Q1 Med Q3 Max -3.74889609 -0.55034466 -0.02516628 0.45341781 3.65746539 Number of Observations: 108 Number of Groups: 27 > and the ANOVA of the lme: > anova(fm2) numDF denDF F-value p-value (Intercept) 1 80 4123.156 <.0001 age 1 80 114.838 <.0001 Sex 1 25 9.292 0.0054 I am confused about that and I did not find any hint in norm, mice/pan/mix or Hmisc. Any help and hints are appreciated, best regards Leo G??rtler / Germany