Does the following answer your question:
> set.seed(1)
> z0 <- rnorm(100)
> p.z <- 2*pnorm(-abs(z0))
> sum(p.z<0.05)
[1] 5
> pchisq(sum(z0^2), 100, lower=FALSE)
[1] 0.917285
Some of the 100 (in this case) normal random deviates seem
statistically significant, even though the ensemble is not.
spencer graves
Arne.Muller at sanofi-aventis.com wrote:
> Hello,
>
> I'm posting this to receive some comments/hints about a rather
statistical than R-technical question ... .
>
> In an anova of a lme factor SSPos11 shows up non-significant,
but in the t-test of the summay 2 of the 4 levels (one for
constrast) are significant. See below for some truncated
output.>
> I realize that the two test are different (F-test/t-test),
but I'm looking for for a "meaning". Maye you have a schenario
that explains how these differences can be created and how you'd
go ahead and analyse it further.>
> When I use SSPos11 as te only fixed effect, it does it is not
significant in either anova nor t-test, and a boxplot of the
factor shows that the levels are all quite similar (similar
variance and mean). Might the effect I observe be linked to
an unbalance design in the multifactorial model?>
> thanks a lot for your help,
> +kind regards,
>
> Arne
>
>
>>anova(fit)
>
> numDF denDF F-value p-value
> (Intercept) 1 540 323.4442 <.0001
> SSPos1 3 540 15.1206 <.0001
> ...
> SSPos11 3 540 1.1902 0.3128
> ...
>
>
>>summary(fit)
>
> Linear mixed-effects model fit by REML
> Data: d.orig
> AIC BIC logLik
> 1007.066 1153.168 -469.5329
>
> Random effects:
> Formula: ~1 | Method
> (Intercept) Residual
> StdDev: 0.4000478 0.4943817
>
> Fixed effects: log(value + 7.5) ~ SSPos1 + SSPos2 + SSPos6 + SSPos7 +
SSPos10 + SSPos11 + SSPos13 + SSPos14 + SSPos18 + SSPos19 +
> Value Std.Error DF t-value p-value
> (Intercept) 2.8621811 0.23125065 540 12.376964 0.0000
> SSPos1C -0.1647937 0.06293993 540 -2.618269 0.0091
> SSPos1G -0.3448095 0.05922479 540 -5.822047 0.0000
> SSPos1T 0.1083988 0.06087095 540 1.780797 0.0755
> ...
> SSPos11C -0.1540292 0.06171635 540 -2.495761 0.0129
> SSPos11G -0.1428980 0.05993122 540 -2.384368 0.0175
> SSPos11T -0.0039434 0.06133920 540 -0.064289 0.9488
> ...
>
>
> [[alternative HTML version deleted]]
>
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Spencer Graves, PhD
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