Hi there. OSX/R2.0 We are trying to implement a bootstrap of the coeffecients of a mixed effect model. In particular, we are interested in the intercept and slope of the random effects. Following from the basics for a linear model, we construct our lme models and a boot function: library(nlme) library(boot) data<-read.csv("~/data.csv") bootcoef<-function(data,index){ dat<-data[index,] mod<-lme(Frames~Man2+Manip+Strings+Date.+Cut.,random=~Man2|ID.,data=dat) fixef(mod) } boot.out<-boot(data,bootcoef,99) boot.ci(boot.out) # produces information via boot.ci() that suggests this is not necessarily successful ORDINARY NONPARAMETRIC BOOTSTRAP Call: boot(data = data, statistic = bootcoef, R = 99) Bootstrap Statistics : original bias std. error t1* 16.125904015 5.299827478 9.98818463 t2* 0.010901682 -0.004134585 0.01621935 t3* -0.038168126 -0.078833467 0.35778286 t4* 1.101486342 -0.021886290 0.45720400 t5* 0.005982241 -0.009140839 0.01563175 t6* 2.729537567 0.287663533 1.56150779 > boot.ci(boot.out) BOOTSTRAP CONFIDENCE INTERVAL CALCULATIONS Based on 99 bootstrap replicates CALL : boot.ci(boot.out = boot.out) Intervals : Level Normal Basic Studentized 95% ( -8.75, 30.40 ) ( -8.40, 36.01 ) (-40.93, 35.15 ) Level Percentile BCa 95% (-3.75, 40.65 ) (-5.55, 28.65 ) Calculations and Intervals on Original Scale Some basic intervals may be unstable Some studentized intervals may be unstable Some percentile intervals may be unstable Warning : BCa Intervals used Extreme Quantiles Some BCa intervals may be unstable Warning messages: 1: NaNs produced in: sqrt(tv[, 2]) 2: Extreme Order Statistics used as Endpoints in: norm.inter(t, adj.alpha) As stated above, we are interested in the ranef(mod) components..... including this instead of fixef(mod) results in the error: > bootcoef<-function(data,index){ + dat<-data[index,] + mod<- lme(Frames~Man2+Manip+Strings+Date.+Cut.+ID.*Man2+ID.*Manip,random=~Man2 |ID.,data=dat) + ranef(mod) + } > > boot.out<-boot(data,bootcoef,99) Error: incorrect number of subscripts on matrix Suggesting that the setup of the ranef(mod) list is different (clearly).... Any suggestions on any of this? I have a sneaking suspicion this is not a straightforward issue. Cheers andrew ------------------------------------------------------------------------ --------- Dr. Andrew Beckerman Department of Animal and Plant Sciences, University of Sheffield, Alfred Denny Building, Western Bank, Sheffield S10 2TN, UK ph +44 (0)114 222 0026; fx +44 (0)114 222 0002 http://www.shef.ac.uk/beckslab ------------------------------------------------------------------------ ----------