Dear all, I would like to raise the question regarding the Intel Itanium processors. Is anyone using them in 64bit mode? I am mostly interested in memory-consuming applications, e.g. the normalization of a large number of microarrays. Andy Liaw told me that he is using R on a dual AMD Opteron in 64bit mode. He can easily allocate 13GB of RAM in a single R process. It would be great if someone in the forum could share his Itanium experiences with respect to that. (OS/compiler issues would also be interesting..) Thanks & best wishes from Vienna, Michael