On Tue, 22 Oct 2002 06:58:47 +0200
Christian Lederer <christianlederer at t-online.de> wrote:
>
> Dear R-gurus,
>
> is there a simple way to simulate of random deviates with a given hazard
function?
> Of course, one could do it by foot by calculating the inverse distribution
function,
> but perhaps someone knows a package which provides this (perhaps using a
more
> elegant method).
>
> Christian :-)
You might take a look at the spower function in the Hmisc library
(http://hesweb1.med.virginia.edu/biostat/s/Hmisc.html) which does this quite
simply by approximating the hazard function over a fine grid to turn the problem
into a simple discrete distribution one. spower does power simulation for
2-sample survival tests under complex conditions such as delated treatment
effect, dropout, dropin, etc.
--
Frank E Harrell Jr Prof. of Biostatistics & Statistics
Div. of Biostatistics & Epidem. Dept. of Health Evaluation Sciences
U. Virginia School of Medicine http://hesweb1.med.virginia.edu/biostat
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