Hi All How can I fit a repeated measures analysis using gls? I want to start with a unstructured correlation structure, as if the the measures at the occations are not longitudinal (no AR) but plainly multivariate (corSymm). My data (ignore the prox_pup and gender, occ means occasion): > head(dta,12) teacher occ prox_self prox_pup gender 1 1 0 0.76 0.41 1 2 1 1 1.00 1.05 1 3 1 3 0.81 0.91 1 4 2 0 0.96 0.64 0 5 3 0 1.12 1.13 1 6 3 2 1.34 1.35 1 7 4 1 0.35 -0.40 0 8 4 2 0.25 0.27 0 9 4 3 0.54 0.26 0 10 5 0 0.65 1.02 1 11 5 1 0.68 0.87 1 12 5 2 1.04 0.98 1 x=factor(dta$occ) Following gives me an error message: gls(prox_pup~x-1, dta, corSymm(, ~x-1|teacher)) > gls(prox_pup~x-1, dta, corSymm(, ~x-1|teacher)) Error in Initialize.corSymm(X[[1]], ...) : Covariate must have unique values within groups for corSymm objects In addition: There were 50 or more warnings (use warnings() to see the first 50) I checked that the covariate, occ, has unique values within each of the teachers. Aside, lme actually gives me what I want, except that the residual variance is not where I want to have it. I want the residuals being part of the covariance matrix to be estimated rather than in the 'level one' residual, ie the residuals included on the diagonal of "G" displayed below. > a4 = lme(prox_pup~x-1, dta, ~x-1|teacher) Linear mixed-effects model fit by REML Data: dta Log-restricted-likelihood: -53.91059 Fixed: prox_pup ~ x - 1 x0 x1 x2 x3 0.5739072 0.7169963 0.6503699 0.6567064 Random effects: Formula: ~x - 1 | teacher Structure: General positive-definite, Log-Cholesky parametrization StdDev Corr x0 0.5424187 x0 x1 x2 x1 0.4326164 0.739 x2 0.3343281 0.611 0.681 x3 0.3638630 0.569 0.752 0.900 Residual 0.0929820 Number of Observations: 153 Number of Groups: 51 > G = lapply(pdMatrix(a4$modelStruct$reStruct), "*", a4$sigma^2) $teacher x0 x1 x2 x3 x0 0.2942180 0.17330375 0.11089028 0.1123597 x1 0.1733037 0.18715693 0.09847681 0.1183089 x2 0.1108903 0.09847681 0.11177526 0.1094374 x3 0.1123597 0.11830892 0.10943738 0.1323963 Thanks for your help on this. Toby