Hi R Community.
I would like to use smooth.spline to fit a set of data and constrain the
endpoints of the fit to have specific derivatives. I know this is
possible with cubic splines, but I can't figure out how to specify this
with arguments to the smooth.spline function. In general, is it possible
to specify a set of "knots" w/locations and derivatives to constrain
the
fit? I can't find anything about this is the documentation.
Thanks!
***********************************
Will Sheffler
Baker Lab
Dept of Genome Sciences
University of Washington
Seattle, WA 98195
