Martin, You got some fine response already from other r-users. Indeed, centering explanatory variables is quite common and it really can have benefits in numerical accuracy. However one might also use centering for response variable and even standardization i.e. x - mean(x) / sd(x). This might increase the robustness of multivariate analysis, where variables have very different scales. For example in biology - agriculture: amount of milk of cows [ from few kg up to 50 kg or even more ] and fat percentage in milk [ around 4% ]. Although, centering of response variables is really not common. -- Lep pozdrav / With regards, Gregor GORJANC --------------------------------------------------------------- University of Ljubljana Biotechnical Faculty URI: http://www.bfro.uni-lj.si Zootechnical Department email: gregor.gorjanc <at> bfro.uni-lj.si Groblje 3 tel: +386 (0)1 72 17 861 SI-1230 Domzale fax: +386 (0)1 72 17 888 Slovenia --------------------------------------------------------------- Message: 52 Date: Fri, 14 Jan 2005 16:44:21 -0500 From: "Martin Julien" <martin.julien.2 at courrier.uqam.ca> Subject: [R] Centered variables and mixed-model To: <r-help at stat.math.ethz.ch> Message-ID: <200501142140.j0ELeJBQ028837 at intrant.uqam.ca> Content-Type: text/plain; charset="iso-8859-1" I work in biology and I use mixed-model for my data analysis In a scientific paper, the author wrote: "All continuous exploratory variables were centred on their median value prior to inclusion in the analysis (Pinheiro & Bates, 2000)." They refer to the book "Mixed-effects model in S and S-Plus" by Pinheiro et Bates in 2000. I feel a bit strange with that paper because I can't find in the book why they centred the variables on their median. So I have two question: First, is it correct to centred the variables on their median in a mixed-model? Second, why they do that? Thank Julien