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-- Bert
On Sat, Mar 23, 2013 at 1:47 PM, Leanna Jones
<leanna_jones@hotmail.com>wrote:
> Hello! I am trying to run a GLMM using LME4, and keep getting the warning
> message: "In mer_finalize(ans) : false convergence (8)" I am
quite new to
> R, and in looking into this thus far, it appears that there are a variety
> of reasons why this might occur, such as needing to standardize some
> parameters or if all subjects in one combination of parameters all have the
> same outcome. I also understand that the warning does not necessarily mean
> that the model results are invalid, but they might be...however, I am
> unsure how to interpret this in my own situation.
> I started with a somewhat more complex model, but kept simplifying it to
> see if I could get the warning to go away (so it might indicate which
> predictor variable was the problem...). However, even when using a single
> fixed effect variable (just sex, for instance), I continue to have the
> problem, which makes me think the issue may be with my random effect. Here
> is the model I would like to run:
>
>
mm1=lmer(BinomialOutcome~AgeGroup+Sex+Study.Site+(1|BearID.reformatted),family=binomial)
> The study is based on bear captures over a period of time, such that some
> bears are captured only once, while others many times (in a very unbalanced
> fashion); I would like to use all the data, but want to account for
> resampling of specific individuals. However, this means that there are
> nearly 600 different bear IDs, and I am wondering if this is the reason why
> the model will not converge? If so, what is the best way to address this?
> Or other ideas as to what might be going on?
> When I run the line above with verbose on, I get the following: >
>
mm1=lmer(BinomialOutcome~AgeGroup+Sex+Study.Site+(1|BearID.reformatted),family=binomial)
> #random effect: Ind with intercept of 1, correcting for the
> intercept/variation btw individuals 0: 805.13676: 1.12717 -0.556586
> 1.85210 2.38794 2.36938 2.35604 -2.22337 1.30764 1.34134 -2.47444
> -1.63320 1: 748.91032: 2.05259 -0.834683 1.81369 2.42567 2.40069
> 2.38217 -2.31535 1.22744 1.26468 -2.64606 -1.74027 2: 723.97734:
> 2.74220 -1.05673 2.00374 2.71876 2.57376 2.50128 -2.73578 1.23505
> 1.35678 -2.98235 -1.63736 3: 715.51275: 2.92015 -1.58830 2.15652
> 3.03669 2.81316 2.67649 -3.28992 1.30372 1.36311 -3.32467 -1.84785 4:
> 696.36424: 3.21244 -1.51265 2.41407 3.41250 3.22182 2.99137
> -3.54075 1.68499 1.83767 -3.33953 -1.80989 5: 672.69327: 4.20847
> -2.35950 3.26463 4.32168 4.39792 4.00460 -3.72829 1.41841 2.56574
> -4.27911 -1.86318 6: 664.48332: 4.37811 -2.58726 3.01153 4.60841
> 4.65061 4.30175 -4.11225 2.30181 2.55998 -4.38222 -2.02300 7:
> 625.68427: 7.31164 -4.89788 5.63003 7.04671 7.95742 8.12903 -4.86511
> 3.64151 3.86169 -6.33864 -2.89485 8: 619.38278: 9.39340 -7.21835
> 5.63590 11.1393 10.6331 11.5975 -4.65786 3.81066 6.58406 -9.13652
> -2.96142 9: 613.14410: 9.53164 -7.17298 6.01739 10.8896 10.7209
> 11.6709 -4.81531 4.06987 6.53556 -9.01013 -3.05630 10: 600.31130:
> 10.0557 -7.29631 7.68818 10.1017 11.1766 12.1945 -5.40073 5.30987
> 6.73629 -8.62503 -3.67308 11: 589.17852: 11.9972 -9.32646 9.77915
> 13.1274 13.2796 14.9828 -6.09763 6.80325 9.19492 -9.58777 -5.25910 12:
> 586.76154: 12.3176 -9.61034 9.97050 13.3227 13.7241 15.3584
> -6.13498 7.19387 9.59990 -9.83274 -5.36590 13: 586.09051: 12.3760
> -9.59270 9.95463 13.2692 13.7816 15.3696 -6.14017 7.35785 9.64404
> -9.83450 -5.34840 14: 585.97813: 12.3886 -9.59431 9.95680 13.2579
> 13.7946 15.3724 -6.14235 7.38957 9.65379 -9.83525 -5.34966 15:
> 585.77123: 12.4143 -9.59929 9.96353 13.2359 13.8209 15.3784 -6.14715
> 7.45208 9.67407 -9.83681 -5.35395 16: 585.69436: 12.4251 -9.60281
> 9.96832 13.2277 13.8318 15.3810 -6.14945 7.47605 9.68290 -9.83747
> -5.35717 17: 585.54933: 12.4469 -9.61094 9.97946 13.2122 13.8536
> 15.3863 -6.15434 7.52306 9.70121 -9.83879 -5.36474 18: 585.49415:
> 12.4558 -9.61507 9.98519 13.2068 13.8624 15.3886 -6.15653 7.54097
> 9.70908 -9.83931 -5.36868 19: 585.38801: 12.4740 -9.62396 9.99753
> 13.1967 13.8800 15.3933 -6.16106 7.57607 9.72529 -9.84034 -5.37720 20:
> 585.38387: 12.4748 -9.62436 9.99809 13.1963 13.8807 15.3935
> -6.16126 7.57741 9.72597 -9.84038 -5.37759 21: 585.35100: 12.4807
> -9.62760 10.0026 13.1936 13.8863 15.3951 -6.16281 7.58812 9.73146
> -9.84070 -5.38074 22: 585.35042: 12.4807 -9.62760 10.0026 13.1936
> 13.8863 15.3951 -6.16281 7.58812 9.73146 -9.87324 -5.38074 23:
> 585.22373: 12.5045 -9.64059 10.0207 13.1830 13.9088 15.4016 -6.16903
> 7.63092 9.75346 -9.87324 -5.39333 24: 585.21879: 12.5055 -9.64113
> 10.0216 13.1827 13.9097 15.4018 -6.16930 7.63249 9.75441 -9.87323
> -5.39392 25: 585.20893: 12.5075 -9.64224 10.0233 13.1822 13.9114
> 15.4024 -6.16984 7.63564 9.75632 -9.87322 -5.39512 26: 585.20499:
> 12.5083 -9.64268 10.0240 13.1820 13.9121 15.4026 -6.17006 7.63689
> 9.75709 -9.87321 -5.39560 27: 585.20420: 12.5085 -9.64277 10.0241
> 13.1820 13.9123 15.4027 -6.17011 7.63714 9.75724 -9.87321 -5.39570 28:
> 585.19792: 12.5098 -9.64349 10.0252 13.1817 13.9134 15.4030
> -6.17046 7.63914 9.75847 -9.87320 -5.39647 29: 585.19767: 12.5098
> -9.64351 10.0253 13.1817 13.9134 15.4030 -6.17047 7.63922 9.75852
> -9.87320 -5.39650 30: 585.19762: 12.5098 -9.64352 10.0253 13.1817
> 13.9135 15.4030 -6.17047 7.63923 9.75853 -9.87320 -5.39651 31:
> 585.19752: 12.5099 -9.64353 10.0253 13.1817 13.9135 15.4030 -6.17048
> 7.63926 9.75855 -9.87320 -5.39652 32: 585.19748: 12.5099 -9.64354
> 10.0253 13.1817 13.9135 15.4030 -6.17048 7.63928 9.75856 -9.87320
> -5.39653 33: 585.19740: 12.5099 -9.64355 10.0253 13.1817 13.9135
> 15.4031 -6.17049 7.63930 9.75857 -9.87320 -5.39654 34: 585.19736:
> 12.5099 -9.64355 10.0253 13.1817 13.9135 15.4031 -6.17049 7.63931
> 9.75858 -9.87320 -5.39654 35: 585.19730: 12.5099 -9.64356 10.0253
> 13.1817 13.9135 15.4031 -6.17049 7.63933 9.75859 -9.87320 -5.39655 36:
> 585.19727: 12.5099 -9.64356 10.0253 13.1817 13.9135 15.4031
> -6.17049 7.63934 9.75860 -9.87320 -5.39655 37: 585.19722: 12.5099
> -9.64356 10.0253 13.1817 13.9135 15.4031 -6.17050 7.63936 9.75861
> -9.87320 -5.39656 38: 585.19719: 12.5099 -9.64363 10.0253 13.1817
> 13.9135 15.4031 -6.17050 7.63936 9.75861 -9.87329 -5.39656 39:
> 585.19679: 12.5100 -9.64367 10.0254 13.1817 13.9136 15.4031 -6.17052
> 7.63949 9.75869 -9.87326 -5.39661 40: 585.19677: 12.5100 -9.64367
> 10.0254 13.1817 13.9136 15.4031 -6.17052 7.63949 9.75869 -9.87326
> -5.39661 41: 585.19677: 12.5100 -9.64367 10.0254 13.1817 13.9136
> 15.4031 -6.17052 7.63949 9.75869 -9.87326 -5.39661 42: 585.19677:
> 12.5100 -9.64367 10.0254 13.1817 13.9136 15.4031 -6.17052 7.63949
> 9.75870 -9.87326 -5.39661 43: 585.19676: 12.5100 -9.64367 10.0254
> 13.1817 13.9136 15.4031 -6.17052 7.63949 9.75870 -9.87326 -5.39661 44:
> 585.19676: 12.5100 -9.64367 10.0254 13.1817 13.9136 15.4031
> -6.17052 7.63949 9.75870 -9.87326 -5.39661 45: 585.19676: 12.5100
> -9.64367 10.0254 13.1817 13.9136 15.4031 -6.17052 7.63949 9.75870
> -9.87326 -5.39661 46: 585.19676: 12.5100 -9.64367 10.0254 13.1817
> 13.9136 15.4031 -6.17052 7.63949 9.75870 -9.87326 -5.39661 47:
> 585.19676: 12.5100 -9.64367 10.0254 13.1817 13.9136 15.4031 -6.17052
> 7.63949 9.75870 -9.87326 -5.39661 48: 585.19676: 12.5100 -9.64367
> 10.0254 13.1817 13.9136 15.4031 -6.17052 7.63949 9.75870 -9.87326
> -5.39661 49: 585.19676: 12.5100 -9.64367 10.0254 13.1817 13.9136
> 15.4031 -6.17052 7.63949 9.75870 -9.87326 -5.39661 50: 585.19676:
> 12.5100 -9.64367 10.0254 13.1817 13.9136 15.4031 -6.17052 7.63949
> 9.75870 -9.87326 -5.39661 51: 585.19676: 12.5100 -9.64367 10.0254
> 13.1817 13.9136 15.4031 -6.17052 7.63949 9.75870 -9.87326 -5.39661 52:
> 585.19676: 12.5100 -9.64367 10.0254 13.1817 13.9136 15.4031
> -6.17052 7.63949 9.75870 -9.87326 -5.39661Warning message:In
> mer_finalize(ans) : false convergence (8)
> I read something on another thread about high values (like the -9.6) being
> a problem here, but I do not completely understand how to interpret or
> address it. The model will run (those results pasted below), and appear
> highly significant, but I do not know to what extent they can be
> trusted...in case it is relevant, I am using the 64-bit version of R
> 2.15.1. (I also tried running it in the 32-bit version, with the same
> outcome.) On another thread I also saw a suggestion about maybe trying a
> development version of R with updates using lme4a(?), but I am not sure
> where/how I would access that. Would this be similar to using the
> pre-release version of R 3.0?
> Any help is greatly appreciated! Thank you!!
> > summary(mm1)Generalized linear mixed model fit by the Laplace
> approximation Formula: BinomialOutcome ~ AgeGroup + Sex + Study.Site + (1 |
> BearID.reformatted) AIC BIC logLik deviance 607.2 662.7 -292.6
> 585.2Random effects: Groups Name Variance Std.Dev.
> BearID.reformatted (Intercept) 156.5 12.51 Number of obs: 1146,
> groups: BearID.reformatted, 546
> Fixed effects: Estimate Std. Error z value Pr(>|z|)
> (Intercept) -9.644 18.171 -0.531 0.59562
> AgeGroupMiddle(6-9) 10.025 1.901 5.273 1.34e-07
> ***AgeGroupOld(10-14) 13.182 2.124 6.207 5.38e-10
> ***AgeGroupOlder(15-19) 13.914 2.270 6.129 8.82e-10
> ***AgeGroupOldest(20-29) 15.403 2.553 6.033 1.61e-09
> ***AgeGroupYearling(0-1) -6.171 2.136 -2.889 0.00387 **
> AgeGroupYoung(4-5) 7.639 1.837 4.159 3.20e-05 ***SexM
> 9.759 2.077 4.700 2.61e-06 ***Study.SiteNorth
> -9.873 18.211 -0.542 0.58770 Study.SiteSouth -5.397
> 18.120 -0.298 0.76584 ---Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’
> 0.05 ‘.’ 0.1 ‘ ’ 1
> Correlation of Fixed Effects: (Intr) AGM(6- AGO(10 AGO(15
> AGO(20 AGY(0- AGY(4- SexM Std.SNAgGrpM(6-9) -0.070
> AgGO(10-14) -0.078 0.842
> AgGO(15-19) -0.078 0.785 0.845
> AgGO(20-29) -0.092 0.695 0.772 0.782
> AgGrpY(0-1) -0.065 0.175 0.164 0.155
> 0.139 AgGrpY(4-5) -0.066 0.917 0.794 0.739
> 0.655 0.173 SexM -0.067 0.142 0.181 0.181
> 0.161 0.022 0.122 Stdy.StNrth -0.987 -0.030 -0.018 -0.012
> 0.009 0.044 -0.031 0.005 Study.StSth -0.993 -0.007 0.003 0.007
> 0.029 0.042 -0.009 0.006 0.991> drop1(mm1,test="Chi") 0:
> 1142.9869: 1.12717 0.112154 0.498078 -1.83237 -1.12752 1: 1081.2050:
> 1.60169 -0.555857 0.193717 -2.08938 -1.53971 2: 1068.5254: 2.45069
> -0.231864 0.438946 -2.11102 -1.20264 3: 1012.1918: 2.79654 -0.963989
> 0.187293 -2.52731 -1.53091 4: 990.71560: 3.62551 -1.36261 0.272242
> -2.90631 -1.58628 5: 985.96908: 3.69185 -1.54796 0.225404 -2.98931
> -1.69633 6: 985.01827: 3.73506 -1.56552 0.230054 -3.00088 -1.70449
> 7: 983.15748: 3.81915 -1.60445 0.237421 -3.02517 -1.72349 8:
> 983.08384: 3.82237 -1.60620 0.237607 -3.02619 -1.72440 9: 982.49663:
> 3.84813 -1.62023 0.239089 -3.03437 -1.73166 10: 982.47321: 3.84916
> -1.62080 0.239144 -3.03470 -1.73195 11: 982.46852: 3.84936 -1.62091
> 0.239155 -3.03477 -1.73201 12: 982.46759: 3.84940 -1.62093 0.239157
> -3.03478 -1.73203 13: 982.46571: 3.84949 -1.62098 0.239162 -3.03481
> -1.73205 14: 982.46497: 3.84952 -1.62100 0.239163 -3.03482 -1.73206
> 15: 982.46482: 3.84953 -1.62100 0.239164 -3.03482 -1.73206 16:
> 982.46452: 3.84954 -1.62101 0.239165 -3.03482 -1.73206 17: 982.46440:
> 3.84954 -1.62101 0.239165 -3.03482 -1.73207 18: 982.46416: 3.84955
> -1.62102 0.239165 -3.03483 -1.73207 19: 982.46415: 3.84956 -1.62102
> 0.239165 -3.03483 -1.73207 20: 982.46413: 3.84956 -1.62102 0.239165
> -3.03483 -1.73207 21: 982.46412: 3.84956 -1.62102 0.239165 -3.03483
> -1.73207 22: 982.46412: 3.84956 -1.62102 0.239165 -3.03483 -1.73207
> 23: 982.46412: 3.84956 -1.62102 0.239165 -3.03483 -1.73207 24:
> 982.46411: 3.84956 -1.62102 0.239165 -3.03483 -1.73207 25: 982.46411:
> 3.84956 -1.62102 0.239165 -3.03483 -1.73207 26: 982.46411: 3.84956
> -1.62102 0.239165 -3.03483 -1.73207 27: 982.46411: 3.84956 -1.62102
> 0.239165 -3.03483 -1.73207 28: 982.46411: 3.84956 -1.62102 0.239165
> -3.03483 -1.73207 29: 982.46411: 3.84956 -1.62102 0.239165 -3.03483
> -1.73207 30: 982.46411: 3.84956 -1.62102 0.239165 -3.03483 -1.73207
> 31: 982.46411: 3.84956 -1.62102 0.239165 -3.03483 -1.73207 32:
> 982.46411: 3.84956 -1.62102 0.239165 -3.03483 -1.73207 33: 982.46411:
> 3.84956 -1.62102 0.239165 -3.03483 -1.73207 34: 982.46411: 3.84956
> -1.62102 0.239165 -3.03483 -1.73207 35: 982.46411: 3.84956 -1.62102
> 0.239165 -3.03483 -1.73207 0: 846.23873: 1.12717 0.278572 1.62294
> 2.11840 1.90947 2.10587 -2.01840 1.06690 -2.73438 -1.74278 1:
> 782.57480: 2.06985 0.0299759 1.59547 2.15616 1.94842 2.13149 -2.10865
> 1.00526 -2.89220 -1.83413 2: 753.61295: 2.70197 -0.340980 1.74779
> 2.41225 2.12259 2.23448 -2.57180 1.01789 -3.23420 -1.87228 3:
> 738.10476: 3.29570 -0.299320 2.03785 2.78902 2.40350 2.40852 -2.96785
> 1.20082 -3.47035 -1.61857 4: 728.66127: 3.31362 -0.914342 2.12930
> 3.06234 2.68853 2.60813 -3.41552 1.29034 -3.76833 -1.96507 5:
> 701.68897: 4.04137 -1.01781 2.69656 3.91014 3.76832 3.42789 -3.74032
> 1.90141 -4.08166 -1.90103 6: 689.12608: 4.84724 -1.55798 3.43921
> 4.54662 4.49161 4.19576 -3.85503 1.53634 -4.97302 -1.68093 7:
> 680.34212: 5.36203 -2.02536 3.05587 5.15610 5.16426 5.04233 -4.05659
> 2.74386 -5.54570 -1.72882 8: 667.22226: 6.08154 -2.37754 4.11778
> 5.54917 5.86894 6.17563 -4.21197 3.03995 -5.76776 -2.09495 9:
> 664.47575: 6.06600 -2.42357 4.64402 6.73615 6.65646 6.86680 -4.26329
> 2.22249 -6.39419 -1.70686 10: 647.69848: 7.74453 -3.47288 5.41815
> 7.92869 8.85059 9.56958 -4.11881 3.26041 -7.77022 -2.09666 11:
> 638.93978: 8.79169 -4.18571 6.99604 10.2563 10.1169 11.9327 -4.92184
> 4.83083 -8.83127 -2.61207 12: 633.33087: 9.53588 -4.77408 8.42878
> 11.1711 12.9052 13.9993 -5.89202 5.96007 -10.5890 -2.36388 13:
> 630.45779: 10.7575 -5.38093 9.48786 12.8797 14.3611 15.6814 -6.19947
> 6.85492 -11.8973 -2.57628 14: 628.17396: 12.0808 -5.93880 11.0813
> 14.7980 15.8619 17.6309 -6.84669 8.14910 -13.8265 -2.62288 15:
> 626.38979: 13.3687 -6.31872 12.6906 16.3895 17.1567 18.9418 -7.49507
> 9.48600 -15.7712 -2.66234 16: 626.07854: 13.3945 -6.28237 12.7024
> 16.3787 17.1587 18.9391 -7.48857 9.50058 -15.7600 -2.63880 17:
> 625.49381: 13.4464 -6.21064 12.7259 16.3558 17.1622 18.9335 -7.47575
> 9.53137 -15.7383 -2.59199 18: 623.67612: 13.6575 -5.93293 12.8203
> 16.2521 17.1718 18.9085 -7.42601 9.66881 -15.6582 -2.40785 19:
> 623.63763: 13.6638 -5.92773 12.8224 16.2477 17.1714 18.9074 -7.42498
> 9.67478 -15.6573 -2.40399 20: 623.34565: 13.7146 -5.88664 12.8388
> 16.2124 17.1678 18.8985 -7.41682 9.72290 -15.6506 -2.37332 21:
> 623.34453: 13.7148 -5.88649 12.8388 16.2123 17.1678 18.8985 -7.41679
> 9.72311 -15.6506 -2.37320 22: 623.34231: 13.7152 -5.88620 12.8390
> 16.2120 17.1677 18.8984 -7.41673 9.72351 -15.6505 -2.37297 23:
> 623.34142: 13.7154 -5.88608 12.8390 16.2118 17.1677 18.8984 -7.41671
> 9.72368 -15.6505 -2.37288 24: 623.33964: 13.7157 -5.88585 12.8391
> 16.2116 17.1677 18.8983 -7.41666 9.72400 -15.6505 -2.37270 25:
> 623.33893: 13.7158 -5.88575 12.8392 16.2115 17.1677 18.8983 -7.41664
> 9.72414 -15.6505 -2.37262 26: 623.33751: 13.7161 -5.88557 12.8392
> 16.2113 17.1677 18.8982 -7.41660 9.72440 -15.6505 -2.37247 27:
> 623.33694: 13.7162 -5.88549 12.8393 16.2113 17.1676 18.8982 -7.41659
> 9.72450 -15.6505 -2.37242 28: 623.33683: 13.7162 -5.88548 12.8393
> 16.2112 17.1676 18.8982 -7.41659 9.72452 -15.6505 -2.37240 29:
> 623.33660: 13.7163 -5.88545 12.8393 16.2112 17.1676 18.8982 -7.41658
> 9.72456 -15.6505 -2.37238 30: 623.33651: 13.7163 -5.88543 12.8393
> 16.2112 17.1676 18.8982 -7.41658 9.72458 -15.6505 -2.37237 31:
> 623.33633: 13.7163 -5.88541 12.8393 16.2112 17.1676 18.8982 -7.41657
> 9.72462 -15.6505 -2.37235 32: 623.33625: 13.7163 -5.88540 12.8393
> 16.2112 17.1676 18.8982 -7.41657 9.72463 -15.6505 -2.37234 33:
> 623.33611: 13.7164 -5.88538 12.8393 16.2112 17.1676 18.8982 -7.41657
> 9.72466 -15.6504 -2.37233 34: 623.33605: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 35:
> 623.33604: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 36: 623.33604: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 37:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 38: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 39:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 40: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 41:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 42: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 43:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 44: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 45:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 46: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 47:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 48: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 49:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 50: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 51:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 52: 623.33603: 13.7164 -5.88537 12.8393
> 16.2111 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 53:
> 623.33603: 13.7164 -5.88537 12.8393 16.2111 17.1676 18.8982 -7.41657
> 9.72467 -15.6504 -2.37232 54: 623.18051: 13.7164 -5.88537 12.8393
> 15.9611 17.1676 18.8982 -7.41657 9.72467 -15.6504 -2.37232 55:
> 623.17193: 13.7182 -5.88422 12.8400 15.9611 17.1676 18.8980 -7.41637
> 9.72650 -15.6504 -2.37129 56: 623.17048: 13.7186 -5.88404 12.8402
> 15.9611 17.1675 18.8980 -7.41638 9.72686 -15.6507 -2.37116 57:
> 623.16693: 13.7192 -5.88342 12.8403 15.9611 17.1674 18.8978 -7.41629
> 9.72752 -15.6506 -2.37069 58: 623.16551: 13.7195 -5.88317 12.8403
> 15.9610 17.1673 18.8977 -7.41625 9.72778 -15.6505 -2.37050 59:
> 623.16522: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72783 -15.6505 -2.37046 60: 623.16522: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 61:
> 623.16520: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 62: 623.16520: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 63:
> 623.16519: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 64: 623.16519: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 65:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 66: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 67:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 68: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 69:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 70: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 71:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 72: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 73:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 74: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 75:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 76: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 77:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 78: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 79:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 80: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 81:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 82: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 83:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 84: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 85:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 86: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 87:
> 623.16518: 13.7196 -5.88312 12.8403 15.9610 17.1673 18.8977 -7.41624
> 9.72784 -15.6505 -2.37046 88: 623.16518: 13.7196 -5.88312 12.8403
> 15.9610 17.1673 18.8977 -7.41624 9.72784 -15.6505 -2.37046 0:
> 825.98095: 1.12717 -2.41703 1.72745 2.29886 2.38549 2.31902 -2.27887
> 1.25352 1.44017 1: 768.06345: 2.07624 -2.69053 1.69566 2.34024
> 2.41265 2.34773 -2.37055 1.17396 1.36650 2: 744.59077: 2.64935
> -3.24446 1.82758 2.59452 2.55449 2.46280 -2.86209 1.12221 1.29582 3:
> 736.99381: 3.31052 -3.04318 2.10131 2.92439 2.77195 2.62569
> -3.08356 1.30064 1.72466 4: 716.74511: 3.35950 -3.72313 2.20986
> 3.22603 3.05744 2.84362 -3.61472 1.44647 1.73457 5: 707.12863:
> 3.89898 -3.87644 2.51353 3.59176 3.42641 3.14595 -3.75592 1.52247
> 2.18869 6: 689.81755: 4.12426 -4.92704 2.63166 4.11921 4.40079
> 4.06922 -3.48138 1.98536 2.86830 7: 683.90531: 4.21462 -5.38729
> 3.16190 4.39849 4.60220 4.33037 -3.99172 1.87999 2.70646 8:
> 675.06843: 4.59730 -5.39681 3.42996 4.74518 4.97995 4.86626 -3.96617
> 2.31903 2.86066 9: 664.23055: 5.07016 -6.40610 3.56999 5.71434
> 5.74554 5.68005 -4.33364 2.24829 3.45485 10: 652.85574: 5.78110
> -8.29863 4.98085 5.94655 7.54105 7.78951 -4.04472 2.82537 4.69931 11:
> 635.98569: 6.73243 -9.86573 6.01804 7.60838 8.72554 9.99925
> -4.38569 4.20022 5.22814 12: 619.31300: 8.70673 -12.4571 7.76927
> 11.4392 12.0721 14.0201 -3.85823 4.87447 7.80232 13: 613.90764:
> 8.97979 -12.6322 7.57432 11.2713 12.1345 13.9846 -4.10848 5.48588
> 7.66889 14: 608.91045: 9.73499 -13.5700 8.10962 11.8333 12.9044
> 14.5777 -4.50807 6.06720 8.37211 15: 608.87892: 9.74003 -13.5711
> 8.11291 11.8313 12.9046 14.5771 -4.51043 6.07105 8.37336 16:
> 608.81647: 9.75010 -13.5733 8.11946 11.8272 12.9050 14.5758 -4.51517
> 6.07875 8.37587 17: 608.81399: 9.75050 -13.5734 8.11972 11.8271
> 12.9050 14.5758 -4.51536 6.07906 8.37597 18: 608.79417: 9.75371
> -13.5741 8.12181 11.8258 12.9052 14.5754 -4.51690 6.08152 8.37679 19:
> 608.79338: 9.75384 -13.5742 8.12189 11.8257 12.9052 14.5754
> -4.51696 6.08161 8.37682 20: 608.79322: 9.75387 -13.5742 8.12191
> 11.8257 12.9052 14.5754 -4.51698 6.08163 8.37683 21: 608.79291:
> 9.75392 -13.5742 8.12194 11.8257 12.9052 14.5753 -4.51700 6.08167
> 8.37684 22: 608.79278: 9.75394 -13.5742 8.12196 11.8257 12.9052
> 14.5753 -4.51701 6.08169 8.37684 23: 608.79253: 9.75398 -13.5742
> 8.12198 11.8257 12.9052 14.5753 -4.51703 6.08172 8.37685 24:
> 608.79243: 9.75400 -13.5742 8.12199 11.8257 12.9052 14.5753 -4.51704
> 6.08173 8.37686 25: 608.79223: 9.75403 -13.5742 8.12202 11.8257
> 12.9052 14.5753 -4.51705 6.08176 8.37687 26: 608.79214: 9.75404
> -13.5742 8.12202 11.8257 12.9052 14.5753 -4.51706 6.08177 8.37687 27:
> 608.79213: 9.75405 -13.5742 8.12203 11.8257 12.9052 14.5753
> -4.51706 6.08177 8.37687 28: 608.79210: 9.75405 -13.5742 8.12203
> 11.8257 12.9052 14.5753 -4.51706 6.08177 8.37687 29: 608.79208:
> 9.75405 -13.5742 8.12203 11.8257 12.9052 14.5753 -4.51706 6.08178
> 8.37687 30: 608.79206: 9.75406 -13.5742 8.12203 11.8257 12.9052
> 14.5753 -4.51707 6.08178 8.37687 31: 608.79205: 9.75406 -13.5742
> 8.12203 11.8257 12.9052 14.5753 -4.51707 6.08178 8.37687 32:
> 608.79204: 9.75406 -13.5742 8.12203 11.8257 12.9052 14.5753 -4.51707
> 6.08178 8.37687 33: 608.79204: 9.75406 -13.5742 8.12203 11.8257
> 12.9052 14.5753 -4.51707 6.08178 8.37687 34: 608.79203: 9.75406
> -13.5742 8.12203 11.8257 12.9052 14.5753 -4.51707 6.08178 8.37688 35:
> 608.79203: 9.75406 -13.5742 8.12203 11.8257 12.9052 14.5753
> -4.51707 6.08178 8.37688 36: 608.79203: 9.75406 -13.5742 8.12204
> 11.8257 12.9052 14.5753 -4.51707 6.08178 8.37688 37: 608.79203:
> 9.75406 -13.5742 8.12204 11.8257 12.9052 14.5753 -4.51707 6.08178
> 8.37688 38: 608.79203: 9.75406 -13.5742 8.12204 11.8257 12.9052
> 14.5753 -4.51707 6.08178 8.37688 39: 608.79203: 9.75406 -13.5742
> 8.12204 11.8257 12.9052 14.5753 -4.51707 6.08178 8.37688 40:
> 608.79203: 9.75406 -13.5742 8.12204 11.8257 12.9052 14.5753 -4.51707
> 6.08178 8.37688 41: 608.79203: 9.75406 -13.5742 8.12204 11.8257
> 12.9052 14.5753 -4.51707 6.08178 8.37688 42: 608.79203: 9.75406
> -13.5742 8.12204 11.8257 12.9052 14.5753 -4.51707 6.08178 8.37688 43:
> 608.79203: 9.75406 -13.5742 8.12204 11.8257 12.9052 14.5753
> -4.51707 6.08178 8.37688 44: 608.79203: 9.75406 -13.5742 8.12204
> 11.8257 12.9052 14.5753 -4.51707 6.08178 8.37688 45: 608.79203:
> 9.75406 -13.5742 8.12204 11.8257 12.9052 14.5753 -4.51707 6.08178
> 8.37688 46: 608.79203: 9.75406 -13.5742 8.12204 11.8257 12.9052
> 14.5753 -4.51707 6.08178 8.37688Single term deletions
> Model:BinomialOutcome ~ AgeGroup + Sex + Study.Site + (1 |
> BearID.reformatted) Df AIC LRT Pr(Chi) <none>
> 607.20 AgeGroup 6 992.46 397.27 < 2.2e-16 ***Sex
> 1 643.17 37.97 7.190e-10 ***Study.Site 2 626.79 23.60 7.522e-06
> ***---Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1
> Warning messages:1: In mer_finalize(ans) : false convergence (8)2: In
> mer_finalize(ans) : false convergence (8)3: In mer_finalize(ans) : false
> convergence (8)>
>
>
> [[alternative HTML version deleted]]
>
>
> ______________________________________________
> R-help@r-project.org mailing list
> https://stat.ethz.ch/mailman/listinfo/r-help
> PLEASE do read the posting guide
> http://www.R-project.org/posting-guide.html
> and provide commented, minimal, self-contained, reproducible code.
>
>
--
Bert Gunter
Genentech Nonclinical Biostatistics
Internal Contact Info:
Phone: 467-7374
Website:
http://pharmadevelopment.roche.com/index/pdb/pdb-functional-groups/pdb-biostatistics/pdb-ncb-home.htm
[[alternative HTML version deleted]]