ejm0091
2012-Feb-21 04:35 UTC
[R] Use probesets with highest baseline expression for differntial gene expression in LIMMA
Hello All, I am relatively new to R. I would like to know if there is a way to alter LIMMA defualt options such that the package instead of averaging signal intensities of probesets selects the probesets with highest baseline expression/highest signal intensity? Any help would be greatly appreciated. Many Thanks. Ekta Jain -- View this message in context: http://r.789695.n4.nabble.com/Use-probesets-with-highest-baseline-expression-for-differntial-gene-expression-in-LIMMA-tp4405967p4405967.html Sent from the R help mailing list archive at Nabble.com.
Martin Morgan
2012-Feb-21 13:12 UTC
[R] Use probesets with highest baseline expression for differntial gene expression in LIMMA
On 02/20/2012 08:35 PM, ejm0091 wrote:> Hello All, > I am relatively new to R. I would like to know if there is a way to alter > LIMMA defualt options such that the package instead of averaging signal > intensities of probesets selects the probesets with highest baseline > expression/highest signal intensity? > > Any help would be greatly appreciated.Hi, Please ask on the Bioconductor mailing list. http://bioconductor.org/help/mailing-list/ Provide more information, e.g., about the chip that you are using, and the work flow that you have tried. Please provide the output of the command sessionInfo(). Martin> Many Thanks. > > Ekta Jain > > -- > View this message in context: http://r.789695.n4.nabble.com/Use-probesets-with-highest-baseline-expression-for-differntial-gene-expression-in-LIMMA-tp4405967p4405967.html > Sent from the R help mailing list archive at Nabble.com. > > ______________________________________________ > R-help at r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code.-- Computational Biology Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N. PO Box 19024 Seattle, WA 98109 Location: M1-B861 Telephone: 206 667-2793