Version 2.2 of coxme has been posted to CRAN, Windows versions and mirrors should appear in due course. This is a major update with three features of note: 1. A non-upwardly compatable change: Extractor functions: beta= fixed effects, b=random effects nlme lme4 coxme <2.2 coxme 2.2 lmekin 2.2 ------------------------------------------------------ beta fixef fixef fixef fixef fixef b ranef ranef ---- ranef ranef var(beta) vcov vcov ---- vcov vcov var(b) VarCorr VarCorr ranef VarCorr VarCorr Notice that "ranef" in the prior release was out of step with everyone else, which became obvious when working on lmekin. Also, the constructs "fit$coef$random" and "fit$coef$fixed" no longer work due to some internal rearrangments. 2. The lmekin function is now part of the package. This is the last portion of the older "kinship" package to be updated; I will be talking to the current maintainer of kinship about making it depreciated. This version of lmekin is both more stable and more capable than the old one. Why use lmekin? It can fit most of the models that lme or lmer can, and uses the same formula notation as lmer. However, if lmer can fit your needs I see no good reason to use lmekin and lots of reasons not to use it (plots, residuals, documentation, ...). The lmekin routine can also fit models with complex user-specified variance structures, however, of which familial kinship correlation matrices are the principle example. 3. More vignettes. Terry Therneau