wine users - Dec 2011 - 'Cannot find' - Persistent error

I just recently installed Wine, and now any time I try to run an .exe file, it
reports back with the same error message, reading
wine: Cannot find L"C://windows//system32//*Name of File*"

I'm not quite sure how to handle this. Has anyone had similar problems?

Hello FlimsyMax,

You have to be in the program's directory to run the program.

example.

in a terminal type:
cd /home/username/.wine/drive_c/Programs\ Files/Myprogram
wine myprogram.exe