My video card is a NVIDIA GT 220 with the 280.13 drivers on Ubuntu 11.04(64-bit) and I'm building W.I.N.E(32-bit version) from source. So how do I compile in OpenCL support you ask? Code: cd /usr/include #make directorty# sudo mkdir CL cd CL #download opencl headers# sudo wget http://www.khronos.org/registry/cl/api/1.1/cl_ext.h sudo wget http://www.khronos.org/registry/cl/api/1.1/cl_gl_ext.h sudo wget http://www.khronos.org/registry/cl/api/1.1/cl_gl.h sudo wget http://www.khronos.org/registry/cl/api/1.1/cl.h sudo wget http://www.khronos.org/registry/cl/api/1.1/cl_platform.h sudo wget http://www.khronos.org/registry/cl/api/1.1/opencl.h #custom configure. nVidia provides 32-bit opencl drivers in /usr/lib32# CC="gcc-4.5 -m32" LDFLAGS="-L/lib32 -L/usr/lib32 -Wl,-rpath,/lib32 -Wl,-rpath,/usr/lib32" OPENCL_LIBS="/usr/lib32" OPENCL_CFLAGS="/usr/include/CL" ./configure -v --prefix=/usr #make make and sudo make install Now you will have OpenCL support in W.I.N.E. NJoy!