wine users - Nov 2009 - help I want to install wine in obuntu

I am quit new in linux, I want to install Mega this software requiere wine
installed first, I have a HP turion 64 so I install obuntu64 9.10, I followed
the instruction to install wine but the terminal send the following message
Could not open file
/var/lib/apt/lists/cr.archive.ubuntu.com_ubuntu_dists_karmic_main_source_Sources
- open (2: No such file or directory)
bernal at bernal-laptop:~$ CC="gcc-4.3 -m32" LDFLAGS="-L/lib32
-L/usr/lib32 -Wl,-rpath,/lib32 -Wl,-rpath,/usr/lib32" ./configure -v
bash: ./configure: No such file or directory
bernal at bernal-laptop:~$ make
make: *** No targets specified and no makefile found.  Stop.
bernal at bernal-laptop:~$ sudo make install
make: *** No rule to make target `install'.  Stop.

I also tried 
ubuntu software center but after click on install appear a message 

This error could be caused by required additional software packages which are
missing or not installable. Futhermore there could be a conflict between
software packages which are not allowed to be installed at the same time.

could someone help me please, and I really appreciate if the answer is very
detailed since I have 3 days with linux, and honestly this has been very hard to
understand to me

thank you

Why so difficult? You don't have to mess with compiling from source under
Ubuntu, and with 9.10, there's even a special precompiled package of the
(almost) latest version!

Open Synaptic package manager, select the wine1.2 to get a recent beta.

Before you do so, open the Software Sources tool and enable all repositories
(universe, restricted, multiverse).

Dear Davince

Finally I was able to run bioedit, however I have not the same luck with mega 4,
the webside said this:

. You must have root or "super user" access privileges in order to
install MEGA for Linux
2. A WINE compatible X11 display is required
3. MEGA 4 LE is currently developed and tested for use on the RedHat based
system only
4. The Help manual for MEGA 4 LE is not available temporally; you can download
the MEGA PDF manual or use the MEGA online manual
5. By downloading MEGA 4 LE, you are agreeing not to redistribute the MEGA 4 LE
software and associated materials partially or fully in any form.

MEGA 4 has been tested succesfully on the following versions of Linux: Red Hat
(Kernel 2.6.20 and 2.6.23) and Ubuntu 7.1. In these operating system versions,
you may use the following Wine releases (0.9.39, 0.9.46, 0.9.55, 0.9.56).
MEGA 4 RPM package can be installed directly on Red Hat versions mentioned
above. In order to install MEGA 4 on Ubuntu, you need to follow two steps.
1. alien ?k package.rpm (you will get a file called package.deb after this
command)
2. dpkg ?i package.deb

Installation Instruction

    The installation of MEGA 4 LE depends on the X kernel that you use. Most of
the time, the installation will start automatically after clicking the Submit
and Download button on this page. Generally, the download window will open with
two options:

Option 1: Open with Software Installer
    By choosing this option, the package manager will guide you through the
installation.
    1. You will be asked to enter your root password
    2. The Installing Packages window will be open: click the Apply button to
start the installation
    3. The installer will check the MEGA dependencies. If the Dependencies Added
window opens, then ck Continue or Install Anyway to install the necessary
dependencies.

I was traying to find mega in wine but I can not find it, I try with alien and I
believe I installed using the terminal and  typing sudo apt-get install alien
dpkg-dev debhelper build-essential

then I download mega which is an rpm file but I was stock here,


if you have any idea I would appreciated very much... thank you[/b]

You could provide the terminal output of the application so either a solution
can be given or the devs can find a new thing to fix.

thanks I  will try it