Hi, I tried to run rpubchem in R 2-12.0 on Fedora 13, after installing XML and RCurl'. The sequence of commands were , just following the paper by Rajarshi Guha. aids <- find.assay.id("lung+cancer+carcinoma") sapply(aids, function(x) get.assay.desc(x)$assay.desc) After quite a while the following message was returned: Warning message: In download.file(url, destfile = tmpdest, method = "internal", mode = "wb", : RxmlNanoFTPGetConnection: failed to create socket What is the meaning and how to fix it? Thank you Andreas