Hi all, I use heatmap.2 for clustering and as you know you can choose between several distance functions and clustering algorithms. Trying all combinations isn't too bad but I have two further parameters and whenever I change one of these I need do redo all cluster combinations. It probably takes weeks to test all possible combinations that's why I would like to use a kind of brute-force solution to test all combinations. One major issue is that I have 20 different cases c1-c20 and I need c1-c5 to be in one cluster and c6-c8 in a different one and so on. So after trying a certain combination I somehow need to check whether the cases fall into the same clusters. Cheers -- View this message in context: http://r.789695.n4.nabble.com/Brute-force-clustering-tp2296897p2296897.html Sent from the R help mailing list archive at Nabble.com.