Dear useRs:
We would like to introduce the "pedgene" package, version 1.2,
available now on CRAN, with a brief manual available as a vignette:
http://cran.r-project.org/web/packages/pedgene/index.html
The pedgene package performs gene-level kernel and burden association tests with
disease status and continuous response
for pedigree data, as described in our recent paper:
Schaid, D. J., McDonnell, S. K., Sinnwell, J. P. and Thibodeau, S. N. (2013),
Multiple Genetic Variant Association
Testing by Collapsing and Kernel Methods With Pedigree or Population Structured
Data. Genet. Epidemiol.,
37: 409-418. doi: 10.1002/gepi.21727
LINK: http://onlinelibrary.wiley.com/doi/10.1002/gepi.21727/abstract
We have received some valuable feedback, and welcome more.
Best,
Jason Sinnwell, MS
Mayo Clinic
Division of Biomedical Statistics and Informatics
200 1st St SW
Rochester MN 55905
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